Cryptogenic stroke (CS) is defined as a subtype of stroke associated with a heterogeneous group of pathogenetic mechanisms that remained undetermined in the course of advanced diagnostic research.One third or fourth of the ischemic strokes is cryptogenic.Paradoxical embolism is considered the important cause of cryptogenic stroke and transient isch

Causal inference methods based on conditional independence construct Markov equivalent graphs and cannot be applied to bivariate cases.The approaches based on independence 4.5 of cause and mechanism state, on the contrary, that causal discovery can be inferred for two observations.In our contribution, we pose a challenge to reconcile these two rese

Liver fibrosis represents the consequences of a sustained wound healing response to chronic liver injuries, and its progression toward cirrhosis is the major cause of liver-related morbidity and mortality worldwide.However, anti-fibrotic treatment remains an unconquered area for drug development.Accumulating evidence indicate that oxidative stress

Electroporation of zygotes represents a rapid alternative to the elaborate pronuclear injection procedure for CRISPR/Cas9-mediated genome editing in mice.However, current protocols for electroporation either require the investment in specialized electroporators or corrosive pre-treatment of zygotes which compromises embryo viability.Here, we descri

The importance of road safety education is widely acknowledged; however, there is a lack of Inspection Cameras consistency in road safety interventions currently being used in UK schools.Furthermore, the majority of road safety educational programmes use knowledgebased methods, which do not necessarily translate to improved behaviour in real traffi